Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9978068 | 0.81 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL19861720 | 0.80 | BCHE (0.31) | — | |
| SCHEMBL9977937 | 0.76 | SMN1; SMN2 (0.40) | TP53POLBSMN1; SMN2MAPT | |
| SCHEMBL19861780 | 0.73 | — | — | |
| SCHEMBL9978077 | 0.69 | MAPT (0.38) | TP53POLBSMN1; SMN2MAPT | |
| SCHEMBL27920618 | 0.69 | CYP3A4 (0.41) | CYP3A4 | |
| SCHEMBL16553288 | 0.68 | CYP3A4 (0.44) | CYP3A4 | |
| SCHEMBL15908556 | 0.68 | — | — | |
| SCHEMBL9940768 | 0.66 | CYP3A4 (0.55) | CYP3A4 | |
| SCHEMBL27920798 | 0.66 | CYP3A4 (0.30) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890178-B2 | Azabenzimidazoles as respiratory syncytial virus antiviral agents | JANSSEN SCIENCES IRELAND UC (IE) | 2018-02-13 | — | — | US | disclosed |