SCHEMBL19861972

SCHEMBL19861972

CCCCCOc1ccsc1Br

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
NR1I2 O75469 1/20 0.38
LMNA P02545 1/20 0.38
CHRM2 P08172 1/20 0.38
CYP3A4 P08684 1/20 0.38
ADRA2A P08913 1/20 0.38
MAPT P10636 1/20 0.38
OPRK1 P41145 1/20 0.38
HTR2B P41595 1/20 0.38
SLC6A3 Q01959 1/20 0.38
KMT2A Q03164 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
NR5A1 Q13285 1/20 0.38
SMPD1 P17405 4/20 0.37
LTA4H P09960 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4185747 0.98 NR5A1 (0.41) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL24158298 0.98 NR5A1 (0.41) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL19328686 0.98 NR5A1 (0.41) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL15655221 0.94 CYP1A2 (0.43) MEN1LMNACYP3A4MAPTKMT2A
SCHEMBL8520184 0.81 MAPT (0.40) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL15989455 0.80
SCHEMBL3103832 0.79 NR5A1 (0.43) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL1279017 0.79 NR5A1 (0.43) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL5133914 0.79 NR5A1 (0.43) MEN1NR1I2LMNACHRM2CYP3A4
SCHEMBL19917300 0.78 PRSS1 (0.35) MEN1LMNACYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180047906-A1 HEXABENZOCORONENE-BASED COMPOUND FOR ORGANIC PHOTOVOLTAIC CELLS UNIVERSITE DE PAU ET DES PAYS DE L'ADOUR (FR) 2018-02-15 US disclosed