Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.36 |
| ▸ | UGCG | Q16739 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19862060 | 0.79 | UGCG (0.46) | CYP3A4ALDH1A1KDM4ECYP2D6HPGD | |
| SCHEMBL19862059 | 0.76 | MEN1 (0.46) | ALDH1A1KDM4EHPGDUGCGMEN1 | |
| SCHEMBL22782815 | 0.74 | CYP1A2 (0.39) | ALDH1A1KDM4ECYP2D6HPGDCYP11B2 | |
| SCHEMBL19862022 | 0.72 | MAPK10 (0.46) | CYP3A4ALDH1A1KDM4ECYP11B2CYP17A1 | |
| SCHEMBL19862027 | 0.71 | CYP3A4 (0.40) | CYP3A4CYP11B2CYP17A1UGCGCYP11B1 | |
| SCHEMBL21261977 | 0.71 | CYP3A4 (0.36) | CYP3A4CYP11B2CYP17A1CYP11B1PGR | |
| SCHEMBL22782767 | 0.70 | CYP1A2 (0.36) | ALDH1A1KDM4ECYP2D6HPGDCYP11B2 | |
| SCHEMBL22782770 | 0.70 | CYP1A2 (0.39) | ALDH1A1KDM4ECYP2D6HPGDCYP11B2 | |
| SCHEMBL1482704 | 0.67 | CYP3A4 (0.51) | CYP3A4CYP11B2CYP17A1CYP11B1TDP2 | |
| SCHEMBL20300730 | 0.66 | PRF1 (0.44) | ALDH1A1KDM4ETDP2SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180044302-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES | BIOMARIN PHARMACEUTICAL INC. | 2018-02-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180044302-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS FOR THE TREATMENT OF DISEASES | GBA1, UGCG, GBA2 | CYP3A4 3339/4885ALDH1A1 1342/4885KDM4E 4557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.