Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 14/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8638697 | 0.90 | SLC6A2 (0.49) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3517022 | 0.82 | SLC6A4 (0.71) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL8970430 | 0.75 | SLC6A2 (0.59) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL8311382 | 0.74 | SLC6A2 (0.41) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3466600 | 0.74 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| Hydrochloric Acid SCHEMBL7674030 | 0.74 | SLC6A2 (0.58) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL16298324 | 0.72 | SLC6A4 (0.76) | SLC6A4SLC6A2SLC6A3KCNH2CYP2D6 | |
| SCHEMBL3466082 | 0.72 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL3466085 | 0.72 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL3467709 | 0.71 | SLC6A4 (0.80) | SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075470-A1 | QUATERNARY PIPERIDINE COMPOUNDS AND USES THEREOF | ASTRAZENECA PHARMACEUTICALS LP (US) | 2011-06-23 | — | — | WO | disclosed |