⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945196 | 0.86 | — | — | |
| SCHEMBL127981 | 0.83 | — | — | |
| SCHEMBL127460 | 0.79 | CYP2C19 (0.32) | — | |
| SCHEMBL3084499 | 0.71 | CYP2C19 (0.39) | — | |
| SCHEMBL3761695 | 0.70 | — | — | |
| SCHEMBL27188788 | 0.67 | — | — | |
| SCHEMBL11553602 | 0.64 | CA1 (0.38) | — | |
| SCHEMBL11325110 | 0.64 | CA1 (0.38) | — | |
| SCHEMBL3421401 | 0.64 | — | — | |
| SCHEMBL18162850 | 0.63 | CNR2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4640688-A1 | AVERMECTIN DERIVATIVE | Meiji Seika Pharma Co., Ltd. (JP) | 2025-10-29 | — | — | EP | disclosed |
| WO-2024135828-A1 | AVERMECTIN DERIVATIVE | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 2024-06-27 | — | — | WO | disclosed |
| EP-3606933-A1 | AVERMECTIN DERIVATIVES AS FXR MODULATORS | Hepagene Therapeutics, Inc. (VG) | 2020-02-12 | — | — | EP | disclosed |
| US-20200031858-A1 | AVERMECTIN DERIVATIVES AS FXR MODULATORS | Hepagene Therapeutics (HK) Limited (HK) | 2020-01-30 | — | — | US | disclosed |
| EP-1435786-B2 | PESTICIDAL FORMULATIONS | ELANCO US INC (US) | 2019-10-16 | — | — | EP | disclosed |
| EP-3488698-A1 | PESTICIDAL FORMULATIONS | Elanco US Inc. (US) | 2019-05-29 | — | — | EP | disclosed |
| WO-2018185684-A1 | AVERMECTIN DERIVATIVES AS FXR MODULATORS | HEPAGENE THERAPEUTICS, INC. (VG) | 2018-10-11 | — | — | WO | disclosed |
| EP-3026048-B1 | Hexahydrobenzofurans and hexahydrochromenes - method for production and their use as fragrance compounds | SYMRISE AG (DE) | 2018-07-25 | — | — | EP | disclosed |
| WO-2016083372-A1 | HEXAHYDROBENZOFURANES AND HEXAHYDROCHROMENES, METHOD FOR THE PRODUCTION THEREFOR AND USE THEREOF AS FRAGRANCE PRODUCTS | SYMRISE AG (DE) | 2016-06-02 | — | — | WO | disclosed |
| EP-3026048-A1 | Hexahydrobenzofurans and hexahydrochromens - method for production and their use as fragrance compounds | Symrise AG (DE) | 2016-06-01 | — | — | EP | disclosed |
| US-20050032716-A1 | Pesticidal formulations | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR COLLATERAL AGENT | 2005-02-10 | — | — | US | disclosed |
| US-6764999-B2 | ADMINISTERING IVERMECTIN, MILBEMYCIN OR AVERMECTIN COMPOUNDS IN PROPYLENE GLYCOL TO INCREASE ANIMAL'S BLOOD LEVELS | Ganado Technologies Corp. | 2004-07-20 | — | — | US | disclosed |
| EP-1435786-A1 | PESTICIDAL FORMULATIONS | ELI LILLY AND COMPANY (US) | 2004-07-14 | — | — | EP | disclosed |
| EP-1274309-A4 | SYNERGISTIC FORMULATIONS | LILLY CO ELI (US) | 2004-04-21 | — | — | EP | disclosed |
| US-20040009929-A1 | Nasal delivery of parasiticides | Ganado Technologies Corp. | 2004-01-15 | — | — | US | disclosed |
| US-20030161854-A1 | Synergistic formulations | ELI LILLY AND COMPANY | 2003-08-28 | — | — | US | disclosed |
| WO-2003051281-A2 | COMPOSITION AND METHOD TO TREAT VIRAL BACTERIAL AND PARASITIC INFECTIONS AND INFESTATIONS | GANADO RESEARCH, L.L.C. (US) | 2003-06-26 | — | — | WO | disclosed |
| WO-2003024223-A1 | PESTICIDAL FORMULATIONS | ELI LILLY AND COMPANY (US) | 2003-03-27 | — | — | WO | disclosed |
| EP-1274309-A1 | SYNERGISTIC FORMULATIONS | ELI LILLY AND COMPANY (US) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001070028-A1 | SYNERGISTIC FORMULATIONS | ELI LILLY AND COMPANY (US) | 2001-09-27 | — | — | WO | disclosed |