SCHEMBL19865136

SCHEMBL19865136

OCCCOCC(O)COCCO

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.47
TSHR P16473 2/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
HTT P42858 2/20 0.41
LPAR5 Q9H1C0 1/20 0.39
THRB P10828 1/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 3/20 0.36
HSD17B10 Q99714 1/20 0.36
SPHK1 Q9NYA1 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2C19 P33261 1/20 0.33
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL351789 0.95 USP2 (0.50) USP2TSHRMAPK1MEN1KMT2A
SCHEMBL24855300 0.91 USP2 (0.53) USP2TSHRMAPK1MEN1KMT2A
SCHEMBL350840 0.89 TSHR (0.53) USP2TSHRMAPK1MEN1KMT2A
SCHEMBL25902360 0.86 USP2 (0.48) USP2TSHRMEN1KMT2AHTT
SCHEMBL58458 0.85 USP2 (0.63) USP2TSHRMEN1KMT2AHTT
SCHEMBL5021533 0.84 MEN1 (0.61) USP2TSHRMAPK1MEN1KMT2A
SCHEMBL3542017 0.84 MEN1 (0.61) USP2TSHRMAPK1MEN1KMT2A
SCHEMBL18251584 0.84 MEN1 (0.61) USP2TSHRMAPK1MEN1KMT2A
SCHEMBL10711302 0.84 TSHR (0.67) USP2TSHRMAPK1MEN1KMT2A
SCHEMBL25902370 0.84 USP2 (0.47) USP2TSHRMEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230002696-A1 FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM SHOWA DENKO K.K. (JP) 2023-01-05 US disclosed
US-10803898-B2 Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium SHOWA DENKO K.K. (JP) 2020-10-13 US disclosed
US-20180047419-A1 FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM SHOWA DENKO K.K. (JP) 2018-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10803898-B2 Fluorine-containing ether compound, lubricant for magnetic recording medium, and magnetic recording medium AFF2, AFF1, AFF4 USP2 4043/4885TSHR 1143/4885MAPK1 119/4885
US-20230002696-A1 FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM AFF1, AFF2, PHOSPHO1 USP2 2172/4885TSHR 1264/4885MAPK1 94/4885
US-20180047419-A1 FLUORINE-CONTAINING ETHER COMPOUND, LUBRICANT FOR MAGNETIC RECORDING MEDIUM, AND MAGNETIC RECORDING MEDIUM AFF1, AFF2, AFF4 USP2 4128/4885TSHR 1275/4885MAPK1 73/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.