Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL494612 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 | |
| SCHEMBL495106 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 | |
| SCHEMBL494231 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 | |
| SCHEMBL494146 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 | |
| SCHEMBL16049088 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 | |
| SCHEMBL17554347 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 | |
| SCHEMBL495766 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 | |
| SCHEMBL20025362 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 | |
| SCHEMBL496032 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 | |
| SCHEMBL494434 | 0.81 | TSHR (0.54) | TSHRLMNAALDH1A1SLC1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855508-B1 | CYCLOSPORIN A ANALOGS | ALLERGAN INC (US) | 2018-02-14 | — | — | EP | disclosed |