Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.33 |
| ▸ | CNKSR1 | Q969H4 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19867226 | 0.74 | CNKSR1 (0.44) | ALOX5PTGS1PTGS2CNKSR1AKT1 | |
| SCHEMBL17213396 | 0.73 | CNKSR1 (0.65) | CNKSR1AKT1ALDH1A1 | |
| SCHEMBL15811489 | 0.59 | CNKSR1 (0.64) | CNKSR1AKT1 | |
| SCHEMBL18148011 | 0.59 | CNKSR1 (0.64) | CNKSR1AKT1 | |
| SCHEMBL17213426 | 0.58 | CNKSR1 (0.65) | CNKSR1AKT1ALDH1A1 | |
| SCHEMBL17211781 | 0.56 | CNKSR1 (0.42) | CNKSR1AKT1ALDH1A1MAPT | |
| SCHEMBL19857081 | 0.56 | CNKSR1 (0.67) | CNKSR1AKT1ALDH1A1 | |
| SCHEMBL19415737 | 0.54 | USP2 (0.38) | ALDH1A1MAPT | |
| SCHEMBL11638313 | 0.52 | MAPT (0.55) | ALDH1A1MAPT | |
| SCHEMBL9072998 | 0.52 | MAPT (0.32) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2931280-B1 | METHODS AND COMPOSITIONS FOR INHIBITING CNKSR1 | PHUSIS THERAPEUTICS INC (US) | 2018-02-14 | — | — | EP | disclosed |