SCHEMBL19867558

SCHEMBL19867558

CCOc1ccc(Cc2cc(C3(OC)OC(CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1

nearest known ligand 0.63

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC5A2 P31639 20/20 0.63
SLC5A1 P13866 9/20 0.60
ADRA2A P08913 1/20 0.60
SLC5A11 Q8WWX8 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28283641 1.00 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL1551581 1.00 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL26788443 1.00 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL23453212 1.00 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL30783573 1.00 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL24923615 1.00 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL30437943 1.00 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL3799163 1.00 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11
SCHEMBL29201212 1.00 SLC5A2 (0.63) SLC5A2SLC5A1ADRA2ASLC5A11
Propylene Glycol SCHEMBL17922853 0.95 SLC5A2 (0.57) SLC5A2SLC5A1ADRA2ASLC5A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018029611-A1 NOVEL PROCESSES FOR PREPARATION OF DAPAGLIFLOZIN OR ITS SOLVATES OR CO-CRYSTALS THEREOF LAURUS LABS LIMITED (IN) 2018-02-15 WO disclosed