Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | TOP2A | P11388 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 3/20 | 0.47 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2520075 | 1.00 | ALB (0.56) | ALBKMT2ASMN1; SMN2RETTOP2A | |
| SCHEMBL29761141 | 1.00 | ALB (0.56) | ALBKMT2ASMN1; SMN2RETTOP2A | |
| SCHEMBL4103854 | 1.00 | ALB (0.56) | ALBKMT2ASMN1; SMN2RETTOP2A | |
| SCHEMBL4108565 | 1.00 | ALB (0.56) | ALBKMT2ASMN1; SMN2RETTOP2A | |
| SCHEMBL2521078 | 1.00 | ALB (0.56) | ALBKMT2ASMN1; SMN2RETTOP2A | |
| SCHEMBL4102835 | 1.00 | ALB (0.56) | ALBKMT2ASMN1; SMN2RETTOP2A | |
| SCHEMBL2514966 | 1.00 | ALB (0.56) | ALBKMT2ASMN1; SMN2RETTOP2A | |
| SCHEMBL4096758 | 1.00 | ALB (0.56) | ALBKMT2ASMN1; SMN2RETTOP2A | |
| SCHEMBL19873140 | 0.99 | KMT2A (0.55) | ALBKMT2ASMN1; SMN2RETTOP2A | |
| SCHEMBL2523999 | 0.95 | KMT2A (0.51) | ALBKMT2ASMN1; SMN2RETTOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753708-B1 | NOVEL SIRTUIN ACTIVATING COMPOUNDS AND METHODS FOR MAKING THE SAME | UNIV BRIGHAM YOUNG (US) | 2018-02-21 | — | — | EP | claimed |