SCHEMBL1987346

SCHEMBL1987346

N[C@@H](CS)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ MME P08473 9/20 0.67
▸ ACE P12821 4/20 0.59
▸ CPA1 P15085 1/20 0.59
▸ ACE2 Q9BYF1 1/20 0.59
▸ SLC7A5 Q01650 1/20 0.55
▸ FOLH1 Q04609 1/20 0.53
▸ NAALAD2 Q9Y3Q0 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1987345 1.00 MME (0.67) MMEACECPA1ACE2SLC7A5
SCHEMBL29761659 1.00 MME (0.67) MMEACECPA1ACE2SLC7A5
SCHEMBL29408691 1.00 MME (0.67) MMEACECPA1ACE2SLC7A5
SCHEMBL30011266 0.97 MME (0.64) MMEACECPA1ACE2SLC7A5
SCHEMBL31025643 0.97 MME (0.64) MMEACECPA1ACE2SLC7A5
SCHEMBL29527395 0.97 MME (0.64) MMEACECPA1ACE2SLC7A5
SCHEMBL30011237 0.97 MME (0.64) MMEACECPA1ACE2SLC7A5
SCHEMBL30011197 0.97 MME (0.64) MMEACECPA1ACE2SLC7A5
SCHEMBL31025645 0.97 MME (0.64) MMEACECPA1ACE2SLC7A5
Trifluoroacetic Acid SCHEMBL31675100 0.94 MME (0.60) MMEACECPA1ACE2SLC7A5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 143 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250121026-A1 COMPOSITIONS AND METHODS FOR TREATING FIBROSIS CEDARS-SINAI MEDICAL CENTER (US) 2025-04-17 — — US claimed
WO-2025043563-A1 PEPTIDE TARGETING SOMATOSTATIN RECEPTOR, DRUG CONJUGATE AND USE THEREOF 主流源生物科技(上海)有限公司 2025-03-06 — — WO claimed
US-20240336654-A1 ANTIMICROBIAL PEPTIDOMIMETICS Universität Zürich (CH) 2024-10-10 — — US claimed
CN-118660707-A Supermolecule self-assembly system 北京睿创康泰医药研究院有限公司 2024-09-17 — — CN claimed
EP-4380689-A1 ANTIMICROBIAL PEPTIDOMIMETICS Basilea Pharmaceutica International AG, Allschwil (CH) 2024-06-12 — — EP claimed
CN-118043339-A Antimicrobial peptidomimetics 巴斯利尔药物阿尔施维尔国际股份公司 2024-05-14 — — CN claimed
CN-116333949-A Engineered bacterium for in-situ synthesis of melanin by tumor and application thereof 华中科技大学 2023-06-27 — — CN claimed
CN-110655553-B ACE inhibitory peptide derived from sesame, preparation method and application thereof in preparation of antihypertensive drugs 河南省农业科学院 2023-02-21 — — CN claimed
WO-2023012319-A1 ANTIMICROBIAL PEPTIDOMIMETICS SPEXIS AG (CH) 2023-02-09 — — WO claimed
US-11547738-B2 Compositions and methods for treating fibrosis CEDARS-SINAI MEDICAL CENTER (US) 2023-01-10 — — US claimed
US-20260117070-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) 2026-04-30 — — US disclosed
US-20260069707-A1 COMBINATION THERAPY WITH ANTIBODY-DRUG CONJUGATES AND HYALURONIDASES HALOZYME, INC. (US) 2026-03-12 — — US disclosed
EP-4687960-A1 METHODS OF HEMATOPOIETIC PRECURSOR CELLS MOBILIZATION BioLineRx Ltd. (IL) 2026-02-11 — — EP disclosed
US-20250346589-A1 RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS UNIV ERASMUS MED CT ROTTERDAM (NL) 2025-11-13 — — US disclosed
WO-2025224720-A1 METHODS OF SELECTING TREATMENT REGIMEN AGAINST SOLID TUMORS BIOLINERX LTD. (IL) 2025-10-30 — — WO disclosed
CN-101235081-A Method for preparing oxytocin WUXI KAILI PHARMACEUTICAL CO L (CN) 2008-08-06 — — CN disclosed
WO-2005027713-A2 COMPOSITIONS, SPLICE VARIANTS AND METHODS RELATING TO COLON SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2005-03-31 — — WO disclosed
WO-2004053077-A2 COMPOSITIONS,SPLICE VARIANTS AND METHODS RELATING TO BREAST SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2004-06-24 — — WO disclosed
WO-2004013311-A2 COMPOSITIONS AND METHODS RELATING TO OVARIAN SPECIFIC GENES AND PROTEINS DIADEXUS, INC. (US) 2004-02-12 — — WO disclosed
WO-2003060121-A9 COMPOSITIONS AND METHODS RELATING TO GASTRIC SPECIFIC GENES AND PROTEINS DIADEXUS INC (US) 2003-10-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250346589-A1 RADIOISOTOPE LABELED SSTR2-AGONISTS WITH LINKERS SSTR2, SSTR5, SSTR1 MME 223/4885ACE 1766/4885CPA1 569/4885
US-20260117070-A1 NEAR-INFRARED FLUORESCENT HEPTAMETHINE DYE CONJUGATES WITH FAVORABLE BLEACHING PROPERTIES CBR1, CBR3, NR2E3 MME 2489/4885ACE 4520/4885CPA1 2372/4885
US-20260069707-A1 COMBINATION THERAPY WITH ANTIBODY-DRUG CONJUGATES AND HYALURONIDASES CD22, CD2, CD44 MME 965/4885ACE 2841/4885CPA1 267/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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