Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20468140 | 0.92 | CFTR (0.64) | CFTR | |
| SCHEMBL16446349 | 0.80 | CFTR (0.83) | CFTR | |
| SCHEMBL20468265 | 0.80 | CFTR (0.65) | CFTR | |
| SCHEMBL16445424 | 0.80 | CFTR (1.00) | CFTR | |
| SCHEMBL16445643 | 0.79 | CFTR (1.00) | CFTR | |
| SCHEMBL16445617 | 0.79 | CFTR (1.00) | CFTR | |
| SCHEMBL16445683 | 0.79 | CFTR (1.00) | CFTR | |
| SCHEMBL16445578 | 0.79 | CFTR (1.00) | CFTR | |
| SCHEMBL20454218 | 0.79 | CFTR (0.70) | CFTR | |
| SCHEMBL18732934 | 0.79 | CFTR (0.70) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9895347-B2 | Compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis | GALAPAGOS NV (BE) | 2018-02-20 | — | — | US | disclosed |