Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 13/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18517473 | 1.00 | ELANE (0.43) | ELANEKMT2AATMAPPCYP2C19 | |
| SCHEMBL20827834 | 0.99 | ELANE (0.44) | ELANEKMT2AATMAPPCYP2C19 | |
| SCHEMBL18699714 | 0.99 | ELANE (0.44) | ELANEKMT2AATMAPPCYP2C19 | |
| SCHEMBL19721773 | 0.95 | ELANE (0.43) | ELANEKMT2AATMAPPCYP2C19 | |
| SCHEMBL18517338 | 0.95 | ELANE (0.43) | ELANEKMT2AATMAPPCYP2C19 | |
| SCHEMBL18468434 | 0.91 | ELANE (0.45) | ELANEKMT2AATMCA2 | |
| SCHEMBL9607894 | 0.91 | ELANE (0.47) | ELANEKMT2AATMAPPCYP2C19 | |
| SCHEMBL9607902 | 0.90 | ELANE (0.48) | ELANEKMT2AATMAPPCYP2C19 | |
| SCHEMBL18493267 | 0.88 | ELANE (0.41) | ELANEAPPCYP2C19CA2 | |
| SCHEMBL18476167 | 0.87 | ELANE (0.47) | ELANEKMT2AATMCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3083408-B1 | FILLING DEVICE AND USE THEREOF FOR FILLING A FLUID | MERCK PATENT GMBH (DE) | 2018-02-21 | — | — | EP | disclosed |