Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | GJB2 | P29033 | 4/20 | 0.45 |
| ▸ | TACR2 | P21452 | 3/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.40 |
| ▸ | CDC25B | P30305 | 5/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.40 |
| ▸ | GJA1 | P17302 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19891630 | 1.00 | NT5E (0.54) | NT5EMAOBGJB2TACR2PTPN1 | |
| SCHEMBL19891635 | 1.00 | NT5E (0.54) | NT5EMAOBGJB2TACR2PTPN1 | |
| SCHEMBL19891483 | 1.00 | NT5E (0.54) | NT5EMAOBGJB2TACR2PTPN1 | |
| SCHEMBL19891479 | 1.00 | NT5E (0.54) | NT5EMAOBGJB2TACR2PTPN1 | |
| SCHEMBL19891487 | 1.00 | NT5E (0.54) | NT5EMAOBGJB2TACR2PTPN1 | |
| SCHEMBL19891566 | 0.94 | NT5E (0.54) | NT5EMAOBGJB2TACR2PTPN1 | |
| SCHEMBL19891581 | 0.93 | NT5E (0.52) | NT5EMAOBGJB2TACR2PTPN1 | |
| SCHEMBL19891478 | 0.93 | NT5E (0.52) | NT5EMAOBGJB2TACR2PTPN1 | |
| SCHEMBL19891484 | 0.93 | NT5E (0.52) | NT5EMAOBGJB2TACR2PTPN1 | |
| SCHEMBL19891512 | 0.93 | NT5E (0.52) | NT5EMAOBGJB2TACR2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018035416-A1 | REAGENTS AND METHODS FOR GLYCOSYLATION | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) | 2018-02-22 | — | — | WO | disclosed |