Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 18/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19876272 | 0.84 | BTK (0.56) | BTKBRD4ENPP1 | |
| SCHEMBL19876288 | 0.77 | BTK (0.67) | BTK | |
| SCHEMBL19876262 | 0.75 | BTK (1.00) | BTK | |
| SCHEMBL24426165 | 0.75 | BTK (0.80) | BTK | |
| SCHEMBL19876257 | 0.75 | BTK (0.69) | BTK | |
| SCHEMBL19876226 | 0.74 | BTK (1.00) | BTK | |
| SCHEMBL19876264 | 0.73 | BTK (1.00) | BTK | |
| SCHEMBL28661321 | 0.73 | BTK (0.57) | BTKBRD4 | |
| SCHEMBL19876243 | 0.73 | BTK (1.00) | BTK | |
| SCHEMBL19876267 | 0.73 | BTK (0.73) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500569-B1 | 2-OXO-IMIDAZOPYRIDINES AS REVERSIBLE BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-05-18 | — | — | EP | disclosed |
| WO-2018035080-A1 | 2-OXO-IMIDAZOPYRIDINES AS REVERSIBLE BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2018-02-22 | — | — | WO | disclosed |