Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.87 |
| ▸ | MAPK13 | O15264 | 17/20 | 0.87 |
| ▸ | MAPK12 | P53778 | 17/20 | 0.87 |
| ▸ | MAPK11 | Q15759 | 17/20 | 0.87 |
| ▸ | ABL1 | P00519 | 1/20 | 0.87 |
| ▸ | LCK | P06239 | 1/20 | 0.87 |
| ▸ | FYN | P06241 | 1/20 | 0.87 |
| ▸ | CSF1R | P07333 | 1/20 | 0.87 |
| ▸ | YES1 | P07947 | 1/20 | 0.87 |
| ▸ | LYN | P07948 | 1/20 | 0.87 |
| ▸ | HCK | P08631 | 1/20 | 0.87 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.87 |
| ▸ | ROS1 | P08922 | 1/20 | 0.87 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.87 |
| ▸ | FGR | P09769 | 1/20 | 0.87 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.87 |
| ▸ | SRC | P12931 | 1/20 | 0.87 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.87 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.87 |
| ▸ | EPHA1 | P21709 | 1/20 | 0.87 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Neflamapimod SCHEMBL29396525 | 0.93 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11ABL1 | |
| Neflamapimod SCHEMBL156367 | 0.93 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11ABL1 | |
| SCHEMBL20885633 | 0.89 | MAPK14 (0.83) | MAPK14MAPK13MAPK12MAPK11ABL1 | |
| SCHEMBL14209102 | 0.87 | MAPK14 (0.81) | MAPK14MAPK13MAPK12MAPK11ABL1 | |
| SCHEMBL12139599 | 0.86 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11ABL1 | |
| SCHEMBL12139590 | 0.85 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11ABL1 | |
| SCHEMBL12139614 | 0.83 | MAPK14 (0.73) | MAPK14MAPK13MAPK12MAPK11ABL1 | |
| SCHEMBL12139571 | 0.82 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11ABL1 | |
| SCHEMBL5635285 | 0.82 | MAPK14 (0.79) | MAPK14MAPK13MAPK12MAPK11ABL1 | |
| SCHEMBL12139584 | 0.81 | MAPK14 (1.00) | MAPK14MAPK13MAPK12MAPK11ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018033543-A1 | METHOD OF PREVENTING OR TREATING HEARING LOSS | SUPPORT-VENTURE GMBH (CH) | 2018-02-22 | — | — | WO | disclosed |