Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 14/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19894785 | 0.92 | CHRM3 (0.49) | CHRM3CHRM2CHRM1CYP2D6TSHR | |
| SCHEMBL19894968 | 0.91 | CHRM3 (0.56) | CHRM3CHRM2CHRM1CYP2D6TSHR | |
| SCHEMBL19894878 | 0.89 | CHRM3 (0.48) | CHRM3CHRM2CHRM1CYP2D6TSHR | |
| SCHEMBL19894894 | 0.87 | CHRM3 (0.55) | CHRM3 | |
| SCHEMBL19894874 | 0.85 | CHRM3 (0.48) | CHRM3CHRM2CHRM1CYP2D6TSHR | |
| SCHEMBL19894957 | 0.85 | CHRM3 (0.49) | CHRM3CHRM2CHRM1CYP2D6TSHR | |
| SCHEMBL19894858 | 0.85 | CHRM3 (0.53) | CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL19894811 | 0.84 | CHRM3 (0.50) | CHRM3CHRM2CHRM1CYP2D6 | |
| SCHEMBL19894997 | 0.84 | CHRM3 (0.52) | CHRM3CHRM2CHRM1CYP2D6TSHR | |
| SCHEMBL8509482 | 0.83 | CHRM3 (0.62) | CHRM3CHRM2CHRM1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928879-B1 | PHENYLETHYLPYRIDINE DERIVATIVES AS PDE4-INHIBITORS AND MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | claimed |