Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 17/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509190 | 0.91 | CHRM3 (0.60) | CHRM3CYP2D6 | |
| SCHEMBL8509192 | 0.91 | CHRM3 (0.60) | CHRM3CYP2D6 | |
| SCHEMBL8509191 | 0.91 | CHRM3 (0.60) | CHRM3CYP2D6 | |
| SCHEMBL19895028 | 0.86 | CHRM3 (0.59) | CHRM3CYP2D6 | |
| SCHEMBL16789091 | 0.85 | CHRM3 (0.66) | CHRM3 | |
| SCHEMBL19894968 | 0.85 | CHRM3 (0.56) | CHRM3CYP2D6 | |
| SCHEMBL12071824 | 0.85 | CHRM3 (0.55) | CHRM3CYP2D6 | |
| SCHEMBL15117624 | 0.85 | CHRM3 (0.55) | CHRM3CYP2D6 | |
| SCHEMBL19895012 | 0.85 | CHRM3 (0.55) | CHRM3CYP2D6 | |
| SCHEMBL15117537 | 0.85 | CHRM3 (0.55) | CHRM3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928879-B1 | PHENYLETHYLPYRIDINE DERIVATIVES AS PDE4-INHIBITORS AND MUSCARINIC RECEPTOR ANTAGONISTS | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | claimed |