Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 7/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19899676 | 0.78 | TDP1 (0.43) | TDP1CTDSP1TAAR1CYP11B1CYP11B2 | |
| SCHEMBL19924450 | 0.75 | TDP1 (0.43) | TDP1CTDSP1TAAR1ABL1CASP3 | |
| SCHEMBL19915692 | 0.72 | SCN9A (0.42) | TDP1CTDSP1TAAR1ABL1CASP3 | |
| SCHEMBL18426214 | 0.66 | CYP2A6 (0.41) | TDP1CTDSP1TAAR1PDE10AGRM5 | |
| SCHEMBL10305281 | 0.65 | ABL1 (0.49) | ABL1CYP11B1CYP11B2GRM5 | |
| SCHEMBL1445169 | 0.64 | ATM (0.56) | CYP11B1CYP11B2 | |
| SCHEMBL29787017 | 0.64 | TDP1 (0.49) | TDP1CTDSP1TAAR1CASP3 | |
| SCHEMBL1382442 | 0.63 | NPC1 (0.56) | CYP11B1CYP11B2CASP3 | |
| SCHEMBL17861316 | 0.63 | CYP2A6 (0.53) | CASP3TDO2PDE10A | |
| SCHEMBL22290188 | 0.63 | CYP17A1 (0.58) | TDP1ABL1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018038667-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2018-03-01 | — | — | WO | disclosed |