Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900259 | 0.97 | EPHX1 (0.62) | EPHX1ALDH1A1HPGDCYP19A1CHRM2 | |
| SCHEMBL31611450 | 0.97 | EPHX1 (0.62) | EPHX1ALDH1A1HPGDCYP19A1CHRM2 | |
| SCHEMBL1171507 | 0.95 | EPHX1 (0.64) | EPHX1ALDH1A1HPGDCYP19A1CHRM2 | |
| SCHEMBL19900196 | 0.94 | EPHX1 (0.57) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL31611494 | 0.87 | EPHX1 (0.51) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL23256074 | 0.85 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL30078348 | 0.85 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL21610579 | 0.85 | EPHX1 (0.58) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL6387314 | 0.85 | EPHX1 (0.61) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 | |
| SCHEMBL16194851 | 0.85 | EPHX1 (0.61) | EPHX1ALDH1A1HPGDCYP19A1TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | claimed |
| EP-3503733-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | Iowa State University Research Foundation, Inc. (US) | 2019-07-03 | — | — | EP | claimed |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-02-14 | — | — | US | claimed |
| WO-2018039376-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-03-01 | — | — | WO | claimed |
| US-20240391864-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2024-11-28 | — | — | US | disclosed |
| EP-4382518-A2 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | Iowa State University Research Foundation, Inc. (US) | 2024-06-12 | — | — | EP | disclosed |
| EP-3503733-B1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2024-03-20 | — | — | EP | disclosed |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | UNIV IOWA STATE RES FOUND INC (US) | 2023-06-08 | — | — | US | disclosed |
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-11-01 | — | — | US | disclosed |
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2022-11-01 | — | — | US | disclosed |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-02-14 | — | — | US | disclosed |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2019-02-14 | — | — | US | disclosed |
| WO-2018039376-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11485701-B2 | Insect repellent compounds and compositions, and methods thereof | C5, CYP51A1, DDT | EPHX1 115/4885ALDH1A1 2604/4885HPGD 799/4885 |
| US-20190047937-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | EPHX1 115/4885ALDH1A1 2604/4885HPGD 799/4885 |
| US-20230174457-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | EPHX1 115/4885ALDH1A1 2604/4885HPGD 799/4885 |
| US-20240391864-A1 | INSECT REPELLENT COMPOUNDS AND COMPOSITIONS, AND METHODS THEREOF | C5, CYP51A1, DDT | EPHX1 115/4885ALDH1A1 2604/4885HPGD 799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.