Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11887084 | 0.87 | PTGS1 (0.43) | PTGS1PTGS2FAAHALDH1A1MEN1 | |
| SCHEMBL19901568 | 0.85 | PTGS1 (0.40) | PTGS1PTGS2FAAHALDH1A1MEN1 | |
| SCHEMBL17347440 | 0.85 | PTGS1 (0.46) | PTGS1PTGS2FAAHALDH1A1MEN1 | |
| SCHEMBL21450341 | 0.84 | PTGS1 (0.64) | PTGS1PTGS2FAAHALDH1A1MEN1 | |
| SCHEMBL2552080 | 0.84 | PTGS1 (0.64) | PTGS1PTGS2FAAHALDH1A1MEN1 | |
| SCHEMBL24581267 | 0.83 | PTGS1 (0.49) | PTGS1PTGS2FAAHALDH1A1MEN1 | |
| SCHEMBL31309882 | 0.83 | PTGS1 (0.49) | PTGS1PTGS2FAAHALDH1A1MEN1 | |
| SCHEMBL30963644 | 0.83 | PTGS1 (0.49) | PTGS1PTGS2FAAHALDH1A1MEN1 | |
| SCHEMBL27175515 | 0.82 | PTGS1 (0.50) | PTGS1PTGS2FAAHALDH1A1MEN1 | |
| SCHEMBL14957180 | 0.80 | PTGS1 (0.68) | PTGS1PTGS2FAAHALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961435-B1 | CONJUGATES COMPRISING CELL-BINDING AGENTS AND CYTOTOXIC AGENTS | IMMUNOGEN INC (US) | 2019-05-01 | — | — | EP | disclosed |
| US-9901647-B2 | Conjugates comprising cell-binding agents and cytotoxic agents | IMMUNOGEN, INC. (US) | 2018-02-27 | — | — | US | disclosed |