⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27954057 | 0.97 | CARM1 (0.39) | — | |
| SCHEMBL1821043 | 0.97 | — | — | |
| SCHEMBL25328825 | 0.91 | — | — | |
| SCHEMBL11501898 | 0.84 | — | — | |
| SCHEMBL8907193 | 0.78 | CARM1 (0.37) | — | |
| SCHEMBL15901482 | 0.78 | CARM1 (0.37) | — | |
| SCHEMBL15901483 | 0.78 | CARM1 (0.37) | — | |
| SCHEMBL7708069 | 0.78 | CARM1 (0.37) | — | |
| SCHEMBL7708152 | 0.78 | CARM1 (0.37) | — | |
| SCHEMBL3302686 | 0.78 | CARM1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10959432-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2021-03-30 | — | — | US | claimed |
| US-20200267986-A1 | Microbiocidal Oxadiazole Derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-08-27 | — | — | US | claimed |
| US-10687533-B2 | Microbiocidal oxadiazole derivatives | SYNGENTA PARTICIPATIONS AG (CH) | 2020-06-23 | — | — | US | claimed |
| EP-1572678-A4 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARM INC (US) | 2008-05-07 | — | — | EP | claimed |
| EP-1572678-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | Elan Pharmaceuticals, Inc. (US) | 2005-09-14 | — | — | EP | claimed |
| WO-2004056319-A2 | SUBSTITUTED N-PHENYL SULFONAMIDE BRADYKININ ANTAGONISTS | ELAN PHARMACEUTICALS INC. (US) | 2004-07-08 | — | — | WO | claimed |
| US-20240166669-A1 | QUINAZOLINE AMINE DERIVATIVES AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. | 2024-05-23 | — | — | US | disclosed |
| EP-4301363-A1 | QUINAZOLINE AMINE DERIVATIVES AS KRAS INHIBITORS | Nikang Therapeutics, Inc. (US) | 2024-01-10 | — | — | EP | disclosed |
| CN-117255684-A | Quinazolinamine derivatives as KRAS inhibitors | 尼坎治疗公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-107573275-A | Cinnamamide derivative | 日本脏器制药株式会社 | 2018-01-12 | — | — | CN | disclosed |
| CN-107427506-A | Inhibitors of low molecular weight protein tyrosine phosphatases and uses thereof | 拉霍拉敏感及免疫学研究所 | 2017-12-01 | — | — | CN | disclosed |
| CN-104884426-A | Cinnamide derivative | NIPPON ZOKI PHARMACEUCTICAL CO LTD | 2015-09-02 | — | — | CN | disclosed |
| US-20140018377-A1 | Aminopropenoates as Fungicides | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-01-16 | — | — | US | disclosed |
| EP-0215435-A1 | 2-Oxa-isocephem compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-03-25 | — | — | EP | disclosed |
| EP-0072620-B1 | 3-METHYLFLAVONE-8-CARBOXYLIC ACID ESTERS | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1985-12-04 | — | — | EP | disclosed |
| EP-0072620-A1 | 3-Methylflavone-8-carboxylic acid esters | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1983-02-23 | — | — | EP | disclosed |
| US-4276296-A | Substituted benzopyrano[3,4-c]pyridines, compositions and use thereof | WARNER-LAMBERT COMPANY (US) | 1981-06-30 | — | — | US | disclosed |
| US-4104402-A | BRONCHODILATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-08-01 | — | — | US | disclosed |
| US-4035512-A | Aminotetralols | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-07-12 | — | — | US | disclosed |
| US-4010202-A | TREATMENT OF ASTHMA AND ARRHYTHMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-03-01 | — | — | US | disclosed |