Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 5/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 4/20 | 0.45 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6051426 | 0.88 | SLC1A1 (0.65) | SLC1A1LTA4HHTTSMN1; SMN2TSHR | |
| SCHEMBL6051430 | 0.88 | SLC1A1 (0.65) | SLC1A1LTA4HHTTSMN1; SMN2TSHR | |
| SCHEMBL27479686 | 0.88 | SLC1A1 (0.65) | SLC1A1LTA4HHTTSMN1; SMN2TSHR | |
| Hydrochloric Acid SCHEMBL3575814 | 0.87 | SLC1A1 (0.63) | SLC1A1LTA4HHTTSMN1; SMN2SLC1A3 | |
| SCHEMBL10678429 | 0.85 | SLC1A1 (0.54) | SLC1A1LTA4HHTTSMN1; SMN2TSHR | |
| SCHEMBL30812376 | 0.85 | SLC1A1 (0.61) | SLC1A1LTA4HHTTSMN1; SMN2SLC1A3 | |
| SCHEMBL27252479 | 0.85 | SMN1; SMN2 (0.48) | SLC1A1HTTSMN1; SMN2TSHRSLC1A3 | |
| SCHEMBL5761389 | 0.83 | SLC1A1 (0.62) | SLC1A1LTA4HTSHRSLC1A3SLC1A2 | |
| SCHEMBL2713781 | 0.83 | SLC1A1 (0.62) | SLC1A1LTA4HTSHRSLC1A3SLC1A2 | |
| SCHEMBL2781638 | 0.83 | SLC1A1 (0.62) | SLC1A1LTA4HTSHRSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902688-B2 | Benzamides and nicotinamides as Syk modulators | PORTOLA PHARMACEUTICALS, INC. (US) | 2018-02-27 | — | — | US | disclosed |