SCHEMBL19901901

SCHEMBL19901901

Bc1c(B)c(B)c(-c2nc(-c3cccc(Br)c3)nc3ccccc23)c(B)c1B

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 6/20 0.49
ABCB1 P08183 2/20 0.49
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
ATM Q13315 2/20 0.43
NPC1 O15118 2/20 0.43
TSHR P16473 2/20 0.43
RAB9A P51151 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
MAPT P10636 2/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
HTT P42858 1/20 0.43
HMOX1 P09601 1/20 0.42
ABCC1 P33527 1/20 0.41
GBA1 P04062 2/20 0.41
BIRC5 O15392 1/20 0.40
TP53 P04637 1/20 0.40
CYP1A2 P05177 2/20 0.40
CYP1A1 P04798 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30288945 0.86 MEN1 (0.58) ABCG2ABCB1MEN1KMT2AATM
SCHEMBL12125144 0.86 MEN1 (0.58) ABCG2ABCB1MEN1KMT2AATM
SCHEMBL19901848 0.85 CYP1B1 (0.56) ABCG2ABCB1MEN1KMT2AATM
SCHEMBL23327975 0.83 MEN1 (0.55) ABCG2ABCB1MEN1KMT2AATM
SCHEMBL16231232 0.83 MEN1 (0.59) ABCG2ABCB1MEN1KMT2AATM
SCHEMBL19786353 0.83 ABCG2 (0.59) ABCG2ABCB1MEN1KMT2AATM
SCHEMBL16231233 0.82 ABCG2 (0.52) ABCG2ABCB1MEN1KMT2AATM
SCHEMBL16218730 0.82 ABCG2 (0.52) ABCG2ABCB1MEN1KMT2AATM
SCHEMBL19901896 0.81 ABCG2 (0.47) ABCG2
SCHEMBL19901873 0.81 BIRC5 (0.38) ABCG2ABCB1MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9905773-B2 Compound for organic electronic element, organic electronic element using the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2018-02-27 US disclosed