Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.49 |
| ▸ | CRHBP | P24387 | 1/20 | 0.48 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17021975 | 0.92 | KCNH2 (0.80) | KCNH2KMT2AKDM4EMEN1USP2 | |
| Hydrochloric Acid SCHEMBL17006405 | 0.91 | KCNH2 (0.81) | KCNH2KMT2AKDM4EMEN1USP2 | |
| SCHEMBL17018737 | 0.89 | KCNH2 (0.85) | KCNH2KMT2AKDM4EMEN1USP2 | |
| SCHEMBL19902082 | 0.86 | KCNH2 (0.68) | KCNH2KMT2AKDM4EMEN1USP2 | |
| SCHEMBL17021971 | 0.86 | KMT2A (0.62) | KCNH2KMT2AKDM4EMEN1USP2 | |
| SCHEMBL16961216 | 0.86 | KCNH2 (0.79) | KCNH2KMT2AKDM4EMEN1USP2 | |
| Hydrochloric Acid SCHEMBL17006444 | 0.86 | KMT2A (0.62) | KCNH2KMT2AKDM4EMEN1USP2 | |
| SCHEMBL19902083 | 0.83 | KCNH2 (0.64) | KCNH2KMT2AKDM4EMEN1USP2 | |
| SCHEMBL17006319 | 0.83 | KCNH2 (0.77) | KCNH2KMT2AKDM4EMEN1USP2 | |
| SCHEMBL17018726 | 0.83 | KCNH2 (0.74) | KCNH2KMT2AKDM4EMEN1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9902738-B2 | Compounds and methods for preventing, treating and/or protecting against sensory hair cell death | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2018-02-27 | — | — | US | disclosed |