Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | CCR1 | P32246 | 3/20 | 0.42 |
| ▸ | CCR5 | P51681 | 3/20 | 0.42 |
| ▸ | CCR8 | P51685 | 3/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10262377 | 0.79 | KDM4E (0.48) | HTTKDM4ELMNACCR1CCR5 | |
| SCHEMBL17173346 | 0.75 | KDM4E (0.47) | HTTKDM4ELMNACCR1CCR5 | |
| SCHEMBL15980657 | 0.75 | PSMB5 (0.42) | HTTKDM4ELMNACYP1A2TP53 | |
| SCHEMBL13883296 | 0.75 | KDM4E (0.63) | HTTKDM4ELMNACCR1CCR5 | |
| SCHEMBL5148218 | 0.72 | KDM4E (0.54) | HTTKDM4ELMNACCR1CCR5 | |
| SCHEMBL17173347 | 0.72 | KDM4E (0.44) | HTTKDM4ELMNACCR1CCR5 | |
| SCHEMBL17247904 | 0.72 | KDM4E (0.47) | HTTKDM4ELMNACCR1CCR5 | |
| SCHEMBL17173527 | 0.72 | KDM4E (0.44) | HTTKDM4ELMNACCR1CCR5 | |
| SCHEMBL15980681 | 0.72 | PDE1A (0.44) | L3MBTL1NPC1PDE10ARAB9A | |
| SCHEMBL15980602 | 0.71 | LRRK2 (0.40) | PDE10AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9905785-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2018-02-27 | — | — | US | disclosed |