Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 4/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | GBA1 | P04062 | 8/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20223572 | 0.87 | GBA1 (0.44) | HCRTR2HCRTR1GBA1 | |
| SCHEMBL20223573 | 0.77 | PDE2A (0.40) | HCRTR2HCRTR1GBA1KDM4E | |
| SCHEMBL19894022 | 0.71 | GBA1 (0.45) | HCRTR2HCRTR1GBA1 | |
| SCHEMBL19902947 | 0.70 | GBA1 (0.41) | HCRTR2HCRTR1GBA1 | |
| SCHEMBL22383538 | 0.69 | HCRTR1 (0.49) | HCRTR2HCRTR1GBA1KDM4EMAPT | |
| SCHEMBL20212700 | 0.69 | HCRTR1 (0.49) | HCRTR2HCRTR1 | |
| SCHEMBL20212709 | 0.69 | HCRTR1 (0.48) | HCRTR2HCRTR1GBA1 | |
| SCHEMBL19893856 | 0.69 | HCRTR1 (0.62) | HCRTR2HCRTR1 | |
| SCHEMBL19893919 | 0.67 | HCRTR1 (0.55) | HCRTR2HCRTR1GBA1MAPT | |
| SCHEMBL20223577 | 0.67 | HCRTR1 (0.52) | HCRTR2HCRTR1GBA1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287454-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |