Trichloroethane

Trichloroethane

SCHEMBL1990295

CC(Cl)(Cl)Cl.O=COCl

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL1814391 0.89
Ethane SCHEMBL108080 0.81
SCHEMBL102156 0.80
SCHEMBL5078402 0.77
Methane SCHEMBL204080 0.76
SCHEMBL28559195 0.76
Isobutane SCHEMBL454297 0.74
Propane SCHEMBL1420935 0.74
Ethylene SCHEMBL6849353 0.72
Butane SCHEMBL583590 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2788349-A1 KINASE INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2014-10-15 EP disclosed
EP-2788348-A1 KINASE INHIBITORS Chiesi Farmaceutici S.p.A. (IT) 2014-10-15 EP disclosed
US-8609659-B2 Substituted 3,8-diazabicyclo[3.2.1]octane compounds NEUROSCIENZE PHARMANESS S.C.A.R.L. (IT) 2013-12-17 US disclosed
WO-2013083604-A1 KINASE INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2013-06-13 WO disclosed
WO-2013083606-A1 KINASE INHIBITORS CHIESI FARMACEUTICI S.P.A. (IT) 2013-06-13 WO disclosed
EP-2338889-B1 Diazacyclic compounds having affinity for opioid receptors NEUROSCIENZE PHARMANESS S C A R L (IT) 2012-08-29 EP disclosed
EP-2338889-A1 Diazacyclic compounds having affinity for opioid receptors Neuroscienze Pharmaness S.C. A R.L. (IT) 2011-06-29 EP disclosed
US-20110152238-A1 PHARMACEUTICAL COMPOUNDS NEUROSCIENZE PHARMANESS S.C. A.R.L. (IT) 2011-06-23 US disclosed
WO-2008072078-A1 AN IMPROVED PROCESS FOR PREPARING ROSUVASTATIN CACLIUM AUROBINDO PHARMA LIMITED (IN) 2008-06-19 WO disclosed
WO-2007142810-A2 METHODS OF USING LOW-DOSE DOXEPIN FOR THE IMPROVEMENT OF SLEEP SOMAXON PHARMACEUTICALS, INC. (US) 2007-12-13 WO disclosed
EP-0931062-A1 CONJUGATES AND SPECIFIC IMMUNOASSAYS FOR THE METHADONE METABOLITE 2-ETHYLIDINE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE MICROGENICS CORPORATION (US) 1999-07-28 EP disclosed
WO-1998054133-A1 CONJUGATES AND SPECIFIC IMMUNOASSAYS FOR THE METHADONE METABOLITE 2-ETHYLIDINE-1,5-DIMETHYL-3,3-DIPHENYLPYRROLIDINE MICROGENICS CORPORATION (US) 1998-12-03 WO disclosed
EP-0400916-A2 4,5,6,11-Tetrahydrobenzo [6,7]-cycloocta[1,2-b]thiophen-6,11-imines and 6,11-dihydrobenzo[6,7]-cycloocta[1,2-b]thiophen-6,11 imines PFIZER INC. (US) 1990-12-05 EP disclosed