Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 19/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 18/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19903064 | 0.86 | HCRTR1 (0.52) | HCRTR2HCRTR1KCNH2 | |
| SCHEMBL22383487 | 0.85 | HCRTR2 (0.45) | HCRTR2HCRTR1 | |
| SCHEMBL19903039 | 0.85 | HCRTR1 (0.50) | HCRTR2HCRTR1 | |
| SCHEMBL19903058 | 0.84 | HCRTR2 (0.51) | HCRTR2HCRTR1 | |
| SCHEMBL19903009 | 0.84 | HCRTR1 (0.53) | HCRTR2HCRTR1 | |
| SCHEMBL19902980 | 0.84 | HCRTR1 (0.49) | HCRTR2HCRTR1 | |
| SCHEMBL19893953 | 0.83 | HCRTR2 (0.52) | HCRTR2HCRTR1 | |
| SCHEMBL19903006 | 0.83 | HCRTR2 (0.43) | HCRTR2HCRTR1 | |
| SCHEMBL19903099 | 0.81 | HCRTR2 (0.50) | HCRTR2HCRTR1 | |
| SCHEMBL19903018 | 0.81 | HCRTR2 (0.52) | HCRTR2HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3287454-A1 | HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2018-02-28 | — | — | EP | disclosed |