SCHEMBL19903635

SCHEMBL19903635

Cc1cccc(-c2ccc3c(c2)c2ccccc2n3-c2cc(C#N)c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc2-n2c3ccccc3c3cc(-c4cccc(C)c4)ccc32)c1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
AR P10275 6/20 0.45
XDH P47989 1/20 0.35
ENPP1 P22413 1/20 0.35
ICMT O60725 1/20 0.35
PTPN5 P54829 1/20 0.34
ERBB2 P04626 1/20 0.33
MAT2A P31153 1/20 0.32
PDK2 Q15119 1/20 0.32
PGR P06401 1/20 0.32
PTGER4 P35408 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21440728 0.96 AR (0.48) ARXDHENPP1ICMTPTPN5
SCHEMBL22822318 0.95 AR (0.43) ARXDHENPP1ICMTPTPN5
SCHEMBL19903633 0.94 AR (0.45) ARXDHENPP1PTPN5ERBB2
SCHEMBL19917942 0.93 AR (0.36) ARXDHICMTPGRPTGER4
SCHEMBL19918023 0.93 AR (0.36) ARXDHICMTPGRPTGER4
SCHEMBL19912576 0.93 AR (0.47) ARXDHENPP1ICMTPTPN5
SCHEMBL19917814 0.92 AR (0.41) ARXDHICMTPTPN5PTGER4
SCHEMBL19912429 0.91 AR (0.44) ARXDHENPP1ICMTPTPN5
SCHEMBL22822440 0.91 AR (0.46) ARXDHENPP1ICMTPTPN5
SCHEMBL19917805 0.91 AR (0.47) ARXDHENPP1ICMTPTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices CYNORA GMBH (DE) 2019-10-08 US disclosed
EP-3360945-B1 ORGANIC ELECTROLUMINESCENT DEVICE CYNORA GMBH (DE) 2019-04-24 EP disclosed
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed
EP-3287450-A1 ORGANIC MOLECULES, IN PARTICULAR FOR USE IN ORGANIC OPTOELECTRONIC DEVICES CYNORA GMBH (DE) 2018-02-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10439151-B2 Organic molecules, especially for use in organic optoelectronic devices OR10J3, ORC3, AOC3 AR 4190/4885XDH 91/4885ENPP1 4687/4885
US-20180062086-A1 ORGANIC MOLECULES, ESPECIALLY FOR USE IN ORGANIC OPTOELECTRONIC DEVICES OR10J3, ORC3, AOC3 AR 4212/4885XDH 68/4885ENPP1 4717/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.