⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21728895 | 0.80 | — | — | |
| SCHEMBL22109774 | 0.80 | — | — | |
| SCHEMBL21539382 | 0.79 | — | — | |
| SCHEMBL24685529 | 0.78 | — | — | |
| SCHEMBL21148661 | 0.77 | — | — | |
| SCHEMBL501970 | 0.77 | — | — | |
| SCHEMBL17439191 | 0.77 | — | — | |
| SCHEMBL24404217 | 0.77 | — | — | |
| SCHEMBL501971 | 0.77 | — | — | |
| SCHEMBL27725868 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133181-A1 | KRAS INHIBITORS | THERAS, INC. (US) | 2023-07-13 | — | — | WO | disclosed |
| US-20230151039-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-05-18 | — | — | US | disclosed |
| WO-2023081757-A1 | PI3K-ALPHA INHIBITORS AND METHODS OF MAKING AND USING THE SAME | RELAY THERAPEUTICS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| EP-3630744-B1 | PYRAZOLE MAGL INHIBITORS | H LUNDBECK AS (DK) | 2023-01-25 | — | — | EP | disclosed |
| WO-2022256419-A1 | DUAL WNT SIGNALING PATHWAY INHIBITORS AND AMPK ACTIVATORS FOR TREATMENTS OF DISEASE | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2022-12-08 | — | — | WO | disclosed |
| EP-3991730-A1 | NEUROKININ-1 ANTAGONIST | Shanghai Shengdi Pharmaceutical Co., Ltd (CN) | 2022-05-04 | — | — | EP | disclosed |
| US-11274182-B2 | Poly(amic acid), poly(amic acid) solution, polyimide, polyimide film, layered product, flexible device, and production method for polyimide film | KANEKA CORPORATION (JP) | 2022-03-15 | — | — | US | disclosed |
| WO-2021195066-A2 | KCNT1 INHIBITORS AND METHODS OF USE | PRAXIS PRECISION MEDICINES, INC. (US) | 2021-09-30 | — | — | WO | disclosed |
| US-20210098717-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2021-04-01 | — | — | US | disclosed |
| US-20200313095-A1 | COMPOSITION AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2020-10-01 | — | — | US | disclosed |
| EP-2804861-B1 | SUBSTITUTED PYRIMIDINE COMPOUNDS AND THEIR USE AS SYK INHIBITORS | GENOSCO (US) | 2018-02-28 | — | — | EP | disclosed |