Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | CDK4 | P11802 | 1/20 | 0.55 |
| ▸ | CCND1 | P24385 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.47 |
| ▸ | ACACB | O00763 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | GYS1 | P13807 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12163948 | 0.87 | HPGD (0.63) | HPGDTDP1CDK4CCND1MEN1 | |
| SCHEMBL11913144 | 0.84 | HPGD (0.74) | HPGDTDP1CDK4CCND1MEN1 | |
| SCHEMBL2228900 | 0.84 | HPGD (0.59) | HPGDTDP1CDK4CCND1MEN1 | |
| SCHEMBL23417313 | 0.83 | HPGD (0.51) | HPGDTDP1CDK4CCND1MEN1 | |
| SCHEMBL842996 | 0.83 | HPGD (0.54) | HPGDTDP1CDK4CCND1MEN1 | |
| SCHEMBL12677910 | 0.83 | HPGD (0.54) | HPGDTDP1CDK4CCND1MEN1 | |
| SCHEMBL15930096 | 0.83 | HPGD (0.54) | HPGDTDP1CDK4CCND1MEN1 | |
| SCHEMBL2225809 | 0.83 | HPGD (0.54) | HPGDTDP1CDK4CCND1MEN1 | |
| SCHEMBL3646900 | 0.82 | MEN1 (0.51) | CDK4CCND1MEN1KMT2APARP1 | |
| SCHEMBL21413678 | 0.82 | CDK4 (0.56) | HPGDCDK4CCND1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2928890-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARM SPA (IT) | 2018-02-28 | — | — | EP | disclosed |