Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | CA2 | P00918 | 2/20 | 0.69 |
| ▸ | CA7 | P43166 | 2/20 | 0.69 |
| ▸ | CA9 | Q16790 | 2/20 | 0.69 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | TTR | P02766 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | FDPS | P14324 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7769914 | 1.00 | CA12 (0.69) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5059085 | 0.88 | CA12 (0.86) | CA12CA1CA2CA7CA9 | |
| SCHEMBL10939791 | 0.88 | CA12 (0.86) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13957401 | 0.88 | CA12 (0.86) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1260527 | 0.86 | CA12 (0.83) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3143890 | 0.86 | CA12 (0.83) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7772753 | 0.86 | CA12 (0.67) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7750251 | 0.85 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL7750247 | 0.85 | CA12 (0.61) | CA12CA1CA2CA7CA9 | |
| SCHEMBL5052547 | 0.85 | CA12 (0.75) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11524004-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | THE UNIVERSITY OF TOLEDO (US) | 2022-12-13 | — | — | US | disclosed |
| US-20210038571-A1 | Analogs of Proxisome Proliferator Activated Receptor (PPAR) Agonists and Methods of Using the Same | THE UNIVERSITY OF TOLEDO (US) | 2021-02-11 | — | — | US | disclosed |
| US-10776461-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | THE UNIVERSITY OF TOLEDO (US) | 2020-09-15 | — | — | US | disclosed |
| US-20190147147-A1 | Analogs of Proxisome Proliferator Activated Receptor (PPAR) Agonists and Methods of Using the Same | THE UNIVERSITY OF TOLEDO (US) | 2019-05-16 | — | — | US | disclosed |
| EP-2958907-B1 | BENZOTHIOPHENE DERIVATIVES AND COMPOSITIONS THEREOF AS SELECTIVE ESTROGEN RECEPTOR DEGRADERS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190147147-A1 | Analogs of Proxisome Proliferator Activated Receptor (PPAR) Agonists and Methods of Using the Same | PPARG, PPARA, PPARD | CA12 4357/4885CA1 3203/4885CA2 4015/4885 |
| US-11524004-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | PPARG, PPARA, PPARD | CA12 4357/4885CA1 3203/4885CA2 4015/4885 |
| US-10776461-B2 | Analogs of proxisome proliferator activated receptor (PPAR) agonists and methods of using the same | PPARG, PPARA, PPARD | CA12 4357/4885CA1 3203/4885CA2 4015/4885 |
| US-20210038571-A1 | Analogs of Proxisome Proliferator Activated Receptor (PPAR) Agonists and Methods of Using the Same | PPARG, PPARA, PPARD | CA12 4357/4885CA1 3203/4885CA2 4015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.