Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 19/20 | 0.45 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24503292 | 0.98 | UGCG (0.45) | UGCGHRH1CCR3 | |
| SCHEMBL19904446 | 0.94 | UGCG (0.42) | UGCGHRH1CCR3 | |
| SCHEMBL18101716 | 0.94 | UGCG (0.44) | UGCGHRH1CCR3 | |
| SCHEMBL18101717 | 0.94 | UGCG (0.44) | UGCGHRH1CCR3 | |
| SCHEMBL19904534 | 0.92 | UGCG (0.43) | UGCG | |
| SCHEMBL19904682 | 0.92 | UGCG (0.48) | UGCGHRH1CCR3 | |
| SCHEMBL19904473 | 0.90 | UGCG (0.42) | UGCGHRH1CCR3 | |
| SCHEMBL19904617 | 0.90 | UGCG (0.42) | UGCGHRH1CCR3 | |
| SCHEMBL18101722 | 0.88 | UGCG (0.43) | UGCGHRH1CCR3 | |
| SCHEMBL19904520 | 0.88 | UGCG (0.42) | UGCGHRH1CCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063141-B1 | N-(1-HYDROXY-3-(PYRROLIDINYL)PROPAN-2-YL)PYRROLIDINE-3-CARBOXAMIDE DERIVATIVES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | BIOMARIN PHARM INC (US) | 2018-02-28 | — | — | EP | disclosed |