Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | PDE5A | O76074 | 1/20 | 0.37 |
| ▸ | PDE1A | P54750 | 1/20 | 0.37 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.37 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19905978 | 0.86 | PTGDR2 (0.40) | KDM4EPDE5APDE1APDE1BPDE4D | |
| SCHEMBL19906180 | 0.85 | PTGDR2 (0.41) | KDM4EPDE5APDE1APDE1BPDE4D | |
| SCHEMBL19905803 | 0.85 | KDM4E (0.39) | KDM4EPDE5APDE1APDE1BPDE4D | |
| SCHEMBL19906170 | 0.85 | KDM4E (0.41) | KDM4EPDE5APDE1APDE1BPDE4D | |
| SCHEMBL17547120 | 0.85 | KDM4E (0.37) | KDM4EPDE5APDE1APDE1BPDE4D | |
| SCHEMBL19906057 | 0.84 | PTGDR2 (0.37) | KDM4EPDE5APDE1APDE1BPDE4D | |
| SCHEMBL19906010 | 0.84 | KDM4E (0.36) | KDM4EPDE5APDE1APDE1BPDE4D | |
| SCHEMBL19906146 | 0.83 | PTGDR2 (0.36) | KDM4EPDE5APDE1APDE1BPDE4D | |
| SCHEMBL19905884 | 0.83 | KDM4E (0.38) | KDM4EPDE5APDE1APDE1BPDE4D | |
| SCHEMBL19906048 | 0.82 | PTGDR2 (0.38) | KDM4EPDE5APDE1APDE1BPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |