Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GFER | P55789 | 2/20 | 0.37 |
| ▸ | POLQ | O75417 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 3/20 | 0.34 |
| ▸ | CDK8 | P49336 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 4/20 | 0.31 |
| ▸ | WNT1 | P04628 | 1/20 | 0.31 |
| ▸ | CLK2 | P49760 | 1/20 | 0.31 |
| ▸ | CLK3 | P49761 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19906378 | 0.94 | PTGDR2 (0.35) | KDM4EGFERPOLQCACNA1HUSP7 | |
| SCHEMBL19905859 | 0.89 | PTGDR2 (0.37) | KDM4EPOLQCACNA1HUSP7CCNC | |
| SCHEMBL19906374 | 0.84 | POLQ (0.33) | KDM4EPOLQUSP7CCNCCDK8 | |
| SCHEMBL19906023 | 0.84 | PTGDR2 (0.35) | KDM4EPOLQKMT2AALDH1A1 | |
| SCHEMBL17547145 | 0.84 | PTGDR2 (0.35) | KDM4EPOLQCACNA1HUSP7CCNC | |
| SCHEMBL19906180 | 0.84 | PTGDR2 (0.41) | KDM4EPOLQCACNA1HUSP7CCNC | |
| SCHEMBL19906048 | 0.83 | PTGDR2 (0.38) | KDM4EPOLQUSP7KMT2AALDH1A1 | |
| SCHEMBL19906009 | 0.83 | PTGDR2 (0.35) | KDM4EPOLQUSP7CCNCCDK8 | |
| SCHEMBL17547144 | 0.83 | PTGDR2 (0.35) | KDM4EKMT2AALDH1A1 | |
| SCHEMBL19906010 | 0.83 | KDM4E (0.36) | KDM4EPOLQUSP7KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070081-B1 | BENZOTHIAZOL-6-YL ACETIC ACID DERIVATIVES AND THEIR USE FOR TREATING AN HIV INFECTION | GILEAD SCIENCES INC (US) | 2018-02-28 | — | — | EP | disclosed |