Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.71 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19909613 | 0.81 | BPTF (0.47) | BPTFHSD11B1TSHRDPP4KMT2A | |
| SCHEMBL19909619 | 0.80 | BPTF (0.46) | BPTFHSD11B1TSHRDPP4KMT2A | |
| SCHEMBL15600035 | 0.77 | DPP4 (0.45) | BPTFHSD11B1DPP4ALDH1A1GAA | |
| SCHEMBL19909647 | 0.77 | DPP4 (0.45) | BPTFHSD11B1DPP4ALDH1A1GAA | |
| SCHEMBL1788313 | 0.76 | POLB (0.66) | HSD11B1TSHRKMT2AALDH1A1LMNA | |
| SCHEMBL19909608 | 0.76 | DPP4 (0.64) | BPTFHSD11B1DPP4GAADPP8 | |
| SCHEMBL19909609 | 0.76 | DPP4 (0.64) | BPTFHSD11B1DPP4GAADPP8 | |
| SCHEMBL17818866 | 0.75 | POLB (0.50) | TSHRKMT2AALDH1A1GAAMEN1 | |
| SCHEMBL30730737 | 0.75 | DPP4 (0.73) | HSD11B1DPP4DPP8DPP9 | |
| SCHEMBL1038132 | 0.75 | DPP4 (0.73) | HSD11B1DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3122724-B1 | A PROCESS FOR PRODUCING SAXAGLIPTIN | ZENTIVA KS (CZ) | 2018-02-28 | — | — | EP | disclosed |