Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 18/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16702262 | 0.82 | NR1H4 (0.92) | NR1H4POLBMAPT | |
| SCHEMBL19910458 | 0.80 | NR1H4 (0.66) | NR1H4 | |
| SCHEMBL18994755 | 0.79 | NR1H4 (0.81) | NR1H4POLBMAPT | |
| SCHEMBL16709824 | 0.79 | NR1H4 (0.66) | NR1H4 | |
| SCHEMBL16701975 | 0.78 | NR1H4 (1.00) | NR1H4POLBMAPT | |
| SCHEMBL18993366 | 0.77 | NR1H4 (0.72) | NR1H4POLBMAPT | |
| SCHEMBL19910404 | 0.77 | NR1H4 (0.57) | NR1H4MAPT | |
| SCHEMBL16701915 | 0.77 | NR1H4 (0.91) | NR1H4POLBMAPT | |
| SCHEMBL18993364 | 0.76 | NR1H4 (0.81) | NR1H4POLBMAPT | |
| SCHEMBL16702273 | 0.76 | NR1H4 (0.80) | NR1H4POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065738-B1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |