Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 18/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18191592 | 0.84 | NR1H4 (0.79) | NR1H4 | |
| SCHEMBL18198056 | 0.83 | NR1H4 (0.69) | NR1H4 | |
| SCHEMBL16702569 | 0.82 | NR1H4 (0.86) | NR1H4TP53 | |
| SCHEMBL16702798 | 0.82 | NR1H4 (0.72) | NR1H4 | |
| SCHEMBL18191633 | 0.81 | NR1H4 (0.73) | NR1H4 | |
| SCHEMBL16702707 | 0.80 | NR1H4 (0.69) | NR1H4 | |
| SCHEMBL16702312 | 0.80 | NR1H4 (0.65) | NR1H4TP53 | |
| SCHEMBL16702297 | 0.80 | NR1H4 (0.73) | NR1H4TP53 | |
| SCHEMBL18191572 | 0.79 | NR1H4 (0.67) | NR1H4 | |
| SCHEMBL19910500 | 0.79 | NR1H4 (0.65) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3065738-B1 | COMPOSITIONS AND METHODS FOR MODULATING FARNESOID X RECEPTORS | NOVARTIS AG (CH) | 2018-02-28 | — | — | EP | disclosed |