Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.79 |
| ▸ | FGFR3 | P22607 | 14/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15043282 | 0.88 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043254 | 0.84 | FGFR1 (0.85) | FGFR1FGFR3 | |
| Hydrochloric Acid SCHEMBL15020069 | 0.84 | FGFR1 (0.84) | FGFR1FGFR3 | |
| SCHEMBL15023890 | 0.84 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043304 | 0.83 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043279 | 0.83 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043281 | 0.82 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043280 | 0.82 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15043283 | 0.82 | FGFR1 (1.00) | FGFR1FGFR3 | |
| SCHEMBL15023388 | 0.81 | FGFR1 (1.00) | FGFR1FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180055851-A1 | SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE-CONTAINING COMBINATIONS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-03-01 | — | — | US | disclosed |
| US-20180055851-A1 | SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE-CONTAINING COMBINATIONS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180055851-A1 | SUBSTITUTED 2,3-DIHYDROIMIDAZO[1,2-C]QUINAZOLINE-CONTAINING COMBINATIONS | PIK3R5, PIK3R4, PIK3R1 | FGFR1 11/4885FGFR3 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.