SCHEMBL19913259

SCHEMBL19913259

Cc1ccc(-c2ccc3c(c2)c2cc(-c4ccc(C)cc4C)ccc2n3-c2cc(C#N)c(-n3c4ccc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)cc4c4cc(-c5ccc(C(F)(F)F)cc5C(F)(F)F)ccc43)cc2-c2cc(-c3ccccc3)nc(-c3ccccc3)c2)c(C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 3/20 0.37
XDH P47989 1/20 0.34
CYP2C9 P11712 1/20 0.33
SCN9A Q15858 1/20 0.33
KDM4E B2RXH2 5/20 0.33
ALDH1A1 P00352 4/20 0.33
HPGD P15428 4/20 0.33
L3MBTL1 Q9Y468 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
GAA P10253 1/20 0.33
ADORA2A P29274 2/20 0.32
ADORA1 P30542 2/20 0.32
PPARG P37231 1/20 0.32
NCOA2 Q15596 1/20 0.32
NCOA1 Q15788 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
NCOA3 Q9Y6Q9 1/20 0.32
ALOX5AP P20292 2/20 0.32
FEN1 P39748 2/20 0.32
AKR1C3 P42330 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19919793 0.93 AR (0.37) ARXDHCYP2C9SCN9AKDM4E
SCHEMBL22021221 0.91 AR (0.36) ARXDHCYP2C9SCN9AKDM4E
SCHEMBL19913250 0.91 AR (0.38) ARXDHCYP2C9SCN9AKDM4E
SCHEMBL19913246 0.89 KDM4E (0.39) CYP2C9KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL21258735 0.88 AR (0.39) ARXDHCYP2C9SCN9AALOX5AP
SCHEMBL19913321 0.88 KDM4E (0.36) ARCYP2C9SCN9AKDM4EALDH1A1
SCHEMBL19913227 0.88 KDM4E (0.35) XDHKDM4EALDH1A1HPGDL3MBTL1
SCHEMBL19913241 0.88 KDM4E (0.38) CYP2C9KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL19919653 0.87 AR (0.35) ARXDHCYP2C9SCN9AKDM4E
SCHEMBL19913120 0.87 AR (0.35) ARXDHCYP2C9SCN9AALOX5AP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180062085-A1 ORGANIC MOLECULES FOR USE IN OPTOELECTRONIC DEVICES SAMSUNG DISPLAY CO., LTD. (KR) 2018-03-01 US disclosed