Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 20/20 | 0.67 |
| ▸ | PKD1 | P98161 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19914939 | 0.90 | MAP3K14 (0.54) | MAP3K14PKD1 | |
| SCHEMBL20929167 | 0.85 | MAP3K14 (0.65) | MAP3K14PKD1 | |
| SCHEMBL20929430 | 0.83 | MAP3K14 (0.62) | MAP3K14PKD1 | |
| SCHEMBL20929431 | 0.83 | MAP3K14 (0.62) | MAP3K14PKD1 | |
| SCHEMBL20929168 | 0.82 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL19899371 | 0.82 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL19899366 | 0.82 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL19899365 | 0.82 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL19899364 | 0.82 | MAP3K14 (0.64) | MAP3K14PKD1 | |
| SCHEMBL29599607 | 0.82 | MAP3K14 (0.64) | MAP3K14PKD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018037058-A1 | 2-AZABICYCLO[3.1.0]HEXAN-3-ONE DERIVATIVES AND METHODS OF USE | F. HOFFMANN-LA ROCHE AG (CH) | 2018-03-01 | — | — | WO | disclosed |