SCHEMBL19916975

SCHEMBL19916975

Clc1cccc(-c2cccc(-c3cccc(-c4nc(-c5ccccc5)nc(-c5ccc(-c6ccccc6)cc5)n4)c3)c2)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR1I3 Q14994 1/20 0.51
DPP4 P27487 1/20 0.51
TAAR1 Q96RJ0 1/20 0.50
NPC1 O15118 1/20 0.47
TP53 P04637 1/20 0.47
TSHR P16473 1/20 0.47
NFKB1 P19838 1/20 0.47
RAB9A P51151 1/20 0.47
NFKB2 Q00653 1/20 0.47
RELA Q04206 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
ALOX5 P09917 1/20 0.47
ABCG2 Q9UNQ0 2/20 0.47
PDE5A O76074 2/20 0.47
ABCB1 P08183 1/20 0.47
ABCC1 P33527 1/20 0.47
BACE1 P56817 1/20 0.46
MAOB P27338 1/20 0.46
IDO1 P14902 1/20 0.46
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23300317 1.00 NR1I3 (0.51) NR1I3DPP4TAAR1NPC1TP53
SCHEMBL22092339 1.00 NR1I3 (0.51) NR1I3DPP4TAAR1NPC1TP53
SCHEMBL19885953 1.00 NR1I3 (0.51) NR1I3DPP4TAAR1NPC1TP53
SCHEMBL30775127 1.00 NR1I3 (0.51) NR1I3DPP4TAAR1NPC1TP53
SCHEMBL30775097 1.00 NR1I3 (0.51) NR1I3DPP4TAAR1NPC1TP53
SCHEMBL25824763 0.98 NR1I3 (0.53) NR1I3DPP4TAAR1NPC1TP53
SCHEMBL21689807 0.98 DPP4 (0.53) NR1I3DPP4TAAR1NPC1TP53
SCHEMBL30340724 0.98 NR1I3 (0.53) NR1I3DPP4TAAR1NPC1TP53
SCHEMBL18180907 0.98 NR1I3 (0.53) NR1I3DPP4TAAR1NPC1TP53
SCHEMBL18982932 0.96 NR1I3 (0.51) NR1I3DPP4TAAR1NPC1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018038464-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 두산 2018-03-01 WO disclosed