Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21547123 | 0.93 | PTPN5 (0.46) | KIF11PDK2GABRA1GABRG2GABRB3 | |
| SCHEMBL21547121 | 0.93 | PTPN5 (0.43) | KIF11PDK2GABRG2GABRB3GABRA5 | |
| SCHEMBL19942721 | 0.92 | ABCG2 (0.39) | KIF11GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL21547120 | 0.91 | PTPN5 (0.43) | KIF11PDK2PTPN5SYKPDPK1 | |
| SCHEMBL22562280 | 0.90 | MYC (0.42) | KIF11PDK2GABRA1GABRG2GABRB3 | |
| SCHEMBL22760671 | 0.89 | PTPN5 (0.44) | PDK2GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL19942722 | 0.89 | ABCG2 (0.37) | KIF11SYKMYCPDPK1ALDH1A3 | |
| SCHEMBL21546866 | 0.88 | PTPN5 (0.43) | PDK2GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL22562274 | 0.87 | MYC (0.40) | KIF11PDK2GABRA1GABRG2GABRB3 | |
| SCHEMBL22761174 | 0.86 | PTPN5 (0.43) | PDK2GABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504200-B1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| WO-2018037069-A1 | HETEROCYCLICALLY SUBSTITUTED BIPHENYLS, ESPECIALLY FOR USE IN OPTOELECTRONIC APPARATUSES | CYNORA GMBH (DE) | 2018-03-01 | — | — | WO | disclosed |