Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.64 |
| ▸ | CCR1 | P32246 | 3/20 | 0.64 |
| ▸ | CCR5 | P51681 | 3/20 | 0.64 |
| ▸ | CCR8 | P51685 | 3/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | ALPL | P05186 | 1/20 | 0.64 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.64 |
| ▸ | ALPI | P09923 | 1/20 | 0.64 |
| ▸ | ALPG | P10696 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15024091 | 0.95 | KDM4E (0.67) | KDM4ELMNASMN1; SMN2TP53CCR1 | |
| SCHEMBL6419906 | 0.93 | KDM4E (0.58) | KDM4ELMNASMN1; SMN2TP53CCR1 | |
| SCHEMBL30606847 | 0.93 | KDM4E (0.58) | KDM4ELMNASMN1; SMN2TP53CCR1 | |
| SCHEMBL31635769 | 0.91 | KDM4E (0.62) | KDM4ELMNASMN1; SMN2TP53CCR1 | |
| SCHEMBL4367769 | 0.91 | KDM4E (0.62) | KDM4ELMNASMN1; SMN2TP53CCR1 | |
| SCHEMBL22428447 | 0.91 | KDM4E (0.52) | KDM4ELMNASMN1; SMN2TP53CCR1 | |
| SCHEMBL18679980 | 0.90 | KDM4E (0.55) | KDM4ELMNASMN1; SMN2TP53CCR1 | |
| SCHEMBL13202961 | 0.89 | KDM4E (0.69) | KDM4ELMNASMN1; SMN2TP53CCR1 | |
| SCHEMBL26503490 | 0.89 | KDM4E (0.58) | KDM4ELMNASMN1; SMN2TP53CCR1 | |
| SCHEMBL28057386 | 0.88 | CCR1 (0.58) | KDM4ELMNASMN1; SMN2TP53CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001849-B1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS MGLUR2 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-11-26 | — | — | EP | claimed |
| US-10724903-B2 | Polymer encapsulated particles as surface enhanced Raman scattering probes | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2020-07-28 | — | — | US | disclosed |
| CN-105949471-A | Zn (II) coordination polymer as well as preparation method and application thereof | 河南科技学院 | 2016-09-21 | — | — | CN | disclosed |
| EP-2001849-B1 | PYRIDINE AND PYRIMIDINE DERIVATIVES AS MGLUR2 ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2014-11-26 | — | — | EP | disclosed |
| US-20110151586-A1 | POLYMER ENCAPSULATED PARTICLES AS SURFACE ENHANCED RAMAN SCATTERING PROBES | Nanyang Technological Yniversity | 2011-06-23 | — | — | US | disclosed |
| WO-2009142604-A1 | POLYMER ENCAPSULATED PARTICLES AS SURFACE ENHANCED RAMAN SCATTERING PROBES | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2009-11-26 | — | — | WO | disclosed |
| US-5387719-A | Preparation of aldehydes | BASF AKTIENGESELLSCHAFT (DE) | 1995-02-07 | — | — | US | disclosed |