Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 20/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19918898 | 0.93 | PTK2 (0.79) | PTK2 | |
| SCHEMBL23939892 | 0.90 | PTK2 (0.81) | PTK2 | |
| SCHEMBL19918986 | 0.89 | PTK2 (0.78) | PTK2 | |
| SCHEMBL12135501 | 0.89 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12135127 | 0.85 | PTK2 (1.00) | PTK2 | |
| SCHEMBL12137256 | 0.85 | PTK2 (0.80) | PTK2 | |
| SCHEMBL23939829 | 0.85 | PTK2 (0.81) | PTK2 | |
| SCHEMBL12135107 | 0.85 | PTK2 (1.00) | PTK2 | |
| SCHEMBL23939879 | 0.85 | PTK2 (0.80) | PTK2 | |
| SCHEMBL19919084 | 0.84 | PTK2 (0.80) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367800-B1 | SUBSTITUTED PYRIMIDINES FOR THE TREATMENT OF DISEASES SUCH AS CANCER | BOEHRINGER INGELHEIM INT (DE) | 2018-02-28 | — | — | EP | disclosed |