Triaziquone

Triaziquone

SCHEMBL1991925

O=C1C=C(N2CC2)C(=O)C(N2CC2)=C1N1CC1.Oc1cccc2cccnc12.[AlH3].[AlH3]

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.52
ALOX12 P18054 2/20 0.52
TSHR P16473 3/20 0.51
COMT P21964 2/20 0.51
MMP2 P08253 1/20 0.51
CHRM1 P11229 1/20 0.51
ADRA1A P35348 1/20 0.51
METAP2 P50579 1/20 0.51
METAP1 P53582 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
ALDH1A1 P00352 4/20 0.44
LMNA P02545 1/20 0.44
MAPK1 P28482 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP3A4 P08684 1/20 0.44
CYP2D6 P10635 1/20 0.44
HIF1A Q16665 1/20 0.44
GAA P10253 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.38
FABP1 P07148 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triaziquone SCHEMBL312861 1.00 KDM4E (0.52) KDM4EALOX12TSHRCOMTMMP2
Triaziquone SCHEMBL60990 0.99 KDM4E (0.54) KDM4EALOX12TSHRCOMTMMP2
Triaziquone SCHEMBL16818404 0.98 KDM4E (0.52) KDM4EALOX12TSHRCOMTMMP2
Triaziquone SCHEMBL2330689 0.98 KDM4E (0.52) KDM4EALOX12TSHRCOMTMMP2
Triaziquone SCHEMBL4773780 0.98 KDM4E (0.52) KDM4EALOX12TSHRCOMTMMP2
Triaziquone SCHEMBL8664578 0.86 TSHR (0.44) KDM4ETSHRMMP2ALDH1A1LMNA
Triaziquone SCHEMBL17164998 0.86 TSHR (0.44) KDM4ETSHRMMP2ALDH1A1LMNA
Triaziquone SCHEMBL8660724 0.86 TSHR (0.44) KDM4ETSHRMMP2ALDH1A1LMNA
Triaziquone SCHEMBL3240330 0.84 TSHR (0.42) KDM4EALOX12TSHRCOMTMMP2
Triaziquone SCHEMBL1194235 0.82 HTT (0.57) KDM4EALOX12TSHRCOMTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9214647-B2 Organic light emitting diode device SAMSUNG DISPLAY CO., LTD. (KR) 2015-12-15 US disclosed
US-20110147789-A1 ORGANIC LIGHT EMITTING DIODE DEVICE SAMSUNG MOBILE DISPLAY CO., LTD., (KR) 2011-06-23 US disclosed