Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31585029 | 0.83 | EPHX2 (0.44) | EPHX2TRPA1 | |
| SCHEMBL17123795 | 0.83 | EPHX2 (0.54) | FURINEPHX2FFAR4PARP10TRPA1 | |
| SCHEMBL16308651 | 0.83 | FURIN (0.49) | FURINEPHX2FFAR4PARP10 | |
| SCHEMBL20217187 | 0.83 | FURIN (0.49) | FURINEPHX2FFAR4PARP10HRH3 | |
| SCHEMBL20217186 | 0.83 | FURIN (0.49) | FURINEPHX2FFAR4PARP10 | |
| SCHEMBL16292007 | 0.83 | FURIN (0.49) | FURINEPHX2FFAR4PARP10 | |
| SCHEMBL16292008 | 0.83 | FURIN (0.49) | FURINEPHX2FFAR4PARP10 | |
| SCHEMBL16291678 | 0.83 | FURIN (0.49) | FURINEPHX2FFAR4PARP10 | |
| SCHEMBL5383373 | 0.80 | FURIN (0.46) | FURINEPHX2FFAR4PARP10 | |
| SCHEMBL5375836 | 0.80 | FURIN (0.46) | FURINEPHX2FFAR4PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | AHR, TYR, CYP1A1 | FURIN 1643/4885EPHX2 1462/4885FFAR4 3343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.