Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.64 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.64 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.64 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | HINT1 | P49773 | 3/20 | 0.52 |
| ▸ | STING1 | Q86WV6 | 3/20 | 0.50 |
| ▸ | NT5E | P21589 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1762946 | 1.00 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBHPGD | |
| SCHEMBL2675379 | 1.00 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBHPGD | |
| SCHEMBL19938131 | 1.00 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBHPGD | |
| SCHEMBL19941365 | 1.00 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBHPGD | |
| SCHEMBL19938129 | 1.00 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBHPGD | |
| SCHEMBL19941615 | 1.00 | PI4KA (0.64) | PI4KAPI4K2BPI4K2API4KBHPGD | |
| SCHEMBL10118076 | 0.89 | PI4KA (0.59) | PI4KAPI4K2BPI4K2API4KBHPGD | |
| SCHEMBL20149809 | 0.87 | HPGD (0.73) | HPGDHINT1STING1NT5EPDE3B | |
| SCHEMBL2583453 | 0.87 | HPGD (0.73) | HPGDHINT1STING1NT5EPDE3B | |
| SCHEMBL2675833 | 0.86 | RXFP1 (0.57) | PI4KAPI4K2BPI4K2API4KBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111184702-A | Synthesis of β -CD-PEG-G molecule capable of delaying tumor growth and application of β -CD-PEG-G molecule as drug delivery system | 滨州医学院 | 2020-05-22 | — | — | CN | disclosed |
| US-10513520-B2 | Sulfamide and sulfamate inhibitors of hHint1 | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2019-12-24 | — | — | US | disclosed |
| US-20180065965-A1 | SULFAMIDE AND SULFAMATE INHIBITORS OF hHint1 | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2018-03-08 | — | — | US | disclosed |
| CN-105524609-A | Fluorescent probe GH and preparation method and application thereof | DALIAN INST CHEMICAL PHYSICS CAS | 2016-04-27 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10513520-B2 | Sulfamide and sulfamate inhibitors of hHint1 | GRIN1, OPRL1, GRIN3A | PI4KA 4268/4885PI4K2B 4189/4885PI4K2A 4125/4885 |
| US-20180065965-A1 | SULFAMIDE AND SULFAMATE INHIBITORS OF hHint1 | GRIN1, GRIA1, GRIN2A | PI4KA 3944/4885PI4K2B 3784/4885PI4K2A 3650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.