SCHEMBL19923804

SCHEMBL19923804

Oc1c(Br)cc2ccc3cccc4ccc1c2c34

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.50
ERBB2 P04626 1/20 0.50
FYN P06241 1/20 0.50
MAOA P21397 1/20 0.50
ACHE P22303 1/20 0.50
AHR P35869 1/20 0.50
ALDH1A1 P00352 7/20 0.44
HPGD P15428 5/20 0.44
HSD17B10 Q99714 4/20 0.44
CYP3A4 P08684 2/20 0.44
TSHR P16473 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A1 P04798 2/20 0.42
CYP1B1 Q16678 2/20 0.42
KMT2A Q03164 5/20 0.41
MEN1 O00255 3/20 0.41
DNMT1 P26358 1/20 0.41
CACNA1B Q00975 1/20 0.41
APBA1 Q02410 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29831525 0.80 CYP1A2 (0.53) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL557720 0.80 CYP1A2 (0.53) CYP1A2ERBB2FYNMAOAACHE
Pyrene SCHEMBL28151585 0.80 CYP1A2 (0.53) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL1229467 0.80 CYP1A2 (0.53) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL308801 0.79 CYP1A2 (0.57) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL31266564 0.79 CYP1A2 (0.57) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL28671978 0.79 CYP1A2 (0.57) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL31337704 0.79 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL23062728 0.78 CYP1A2 (0.52) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL3179600 0.77 CYP1A2 (0.50) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11318424-B2 Light-driven ion-pumping membrane systems THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-03 US disclosed
WO-2018049061-A1 LIGHT-DRIVEN ION-PUMPING MEMBRANE SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2018-03-15 WO disclosed
US-20180065095-A1 LIGHT-DRIVEN ION-PUMPING MEMBRANE SYSTEMS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-03-08 US disclosed